Ovagen

Substance: Liver-derived peptide bioregulator · Target tissue: Liver — hepatoprotection

Liver bioregulator; the Khavinson-group hepatology papers in the database are the primary record.

Extract counterpart: None established — this compound exists only as a defined synthetic fragment.

Matched publications in database: 3 (EXTRACT 0, SYNTHETIC 0, EXTRACT→SYN 0)

Extract vs synthetic gap: the human outcome data (including the 266-patient mortality cohort) was collected on extracts; vendors sell synthetic fragments. No head-to-head trial exists — evidence does not transfer between them. Details →

Khavinson studies (3 matched, 2012–2021)

Keyword-filtered from the 472-publication database (khavinson.info). EXTRACT/SYNTHETIC tags are title-text heuristics — verification is on the reader. Full tag legend: evidence-tiers.html

[21] Trofimova S.V., Khavinson V.Kh., Trofimov A.V., Dudkov A.V., Attich K. Role of Short Peptides in Maintaining Liver Functional Activity. // EC Gastroenterology and Digestive System. – 2021. – Vol. 8, Iss. 11. – P. 43-47. (2021)untag [PDF]
[24] Khavinson V. Peptides Regulate Gene Expression and Protein Synthesis in Living Nature. // BIT’s 8th Annual International Symposium of Drug Delivery Systems-2018. – Russian Federation, Saint Petersburg. – 19-21.07.2018. – Abstr. Book. – P. 020. (2018)untag
[69] Ryzhak G.A., Khavinson V.Kh., Kozlov L.V., Ryzhak A.P. Geroprotector on the Basis of the Liver Peptide. // 2nd International Congress on Gerontology and Geriatric Medicine. - New Delhi, India. - 2012. - Journal of the Indian Academy of Geriatrics: abstr. - Vol. 8, Suppl. 1. - P. 23. (2012)untag

Independent (non-Khavinson) studies

None catalogued. To date there are zero independent Western human trials of any Khavinson compound, in any year. Independent in-vitro data exists for Epitalon only (two 2025 studies). If a study belongs here, add it to non-khavinson-research.json and rebuild.

Reddit meta-scrape

No Reddit community discussion exists for this compound. This is honest reporting — the peptide has essentially zero anecdotal footprint in the biohacking community. Absence of anecdotes is not evidence of safety or efficacy, but it does mean there is no community-level signal to analyze.

Measurement protocol — concrete testable endpoints

Liver panel (ALT/AST/GGT), hepatic ultrasound.

All endpoints on one page: measurement-protocols.html · Evidence-tier legend: evidence-tiers.html

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