A public reference archive of published research on short-chain peptide bioregulators — the life work of Prof. Vladimir Khavinson (1946–2024), St. Petersburg Institute of Bioregulation and Gerontology.
472 publications (1979–2023). Zero Western human RCTs. One cohort behind every mortality claim. Every publication is tagged by substance type; every peptide page lists what could actually be measured to test the claims.
| Tag | Meaning | What it can prove / what it can't |
|---|---|---|
| EXTRACT | Biological extract from animal tissue (Epithalamin, Thymalin, Cortexin, Retinalamin). Russian-registered drugs. | Can: anchor the only human outcome data that exists (uncontrolled, single-institution). Can't: be randomized, blinded, or independently replicated. |
| SYNTHETIC | Defined 2–4 amino-acid peptide from solid-phase synthesis. What vendors sell globally. | Can: show in-vitro mechanism (mostly from Khavinson's own institute; two independent Western in-vitro papers for Epitalon, 2025). Can't: inherit the extract's human outcome data — zero Western human RCTs. |
| EXTRACT→SYN | Derivation paper: identifies the active fragment inside the extract complex (e.g. Kopylov 2017, AEDG within pineal complex). | Can: establish lineage. Can't: establish equivalence — no head-to-head extract-vs-synthetic trial exists for any pair. |
| untagged | Title text gives no signal either way. | Treat as unclassified. Heuristic tagging — read the abstract before citing. |
Corpus-wide tag counts: EXTRACT 104 · SYNTHETIC 93 · EXTRACT→SYN 2 · untagged 273
→ Details and the FDA ruling: evidence-tiers.html