Chonluten (EDG) — Khavinson Peptide Research Archive

Bronchial-mucosa tripeptide; the same EDG sequence that is part of the AEDG (Epitalon) tetrapeptide.

Extract counterpart: None established — this compound exists only as a defined synthetic fragment.

Extract vs synthetic gap: the human outcome data (including the 266-patient mortality cohort) was collected on extracts; vendors sell synthetic fragments. No head-to-head trial exists — evidence does not transfer between them. Details →

Khavinson studies (6 matched, 2011–2022)

Keyword-filtered from the 472-publication database (khavinson.info). EXTRACT/SYNTHETIC tags are title-text heuristics — verification is on the reader. Full tag legend: evidence-tiers.html

[5] [Gutop E.O., Linkova N.S., Kozhevnikova E.O., Fridman N.V., Ivko O.M., Khavinson V.Kh. AEDG Peptide Prevents Oxidative Stress in the Model of Induced Aging of Skin Fibroblasts. // Advances in Gerontology. – 2022. – Vol. 12, No. 2. – P. 143-148.](https://khavinson.info/assets/files/skan/2022-gutop.pdf) DOI: 10.1134/S2079057022020096 (2022)syn DOI:10.1134/S2079057022020096 [PDF]

[15] Khavinson V., Linkova N., Ivko O. AEDG Peptide Regulates the Expression of Circadian Genes Clock, Cry2, Csnk1e in Human Immune Cells. // World Heart Journal. – 2021. – Vol. 13, Iss. 1. – P. 189-191. (2021)untag [PDF]

[25] [Khavinson V., Diomede F., Mironova E., Linkova N., Trofimova S., Trubiani O., Caputi S., Sijari B. AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Posible Epigenetic Mechanism. // Molecules. – 2020. – Vol. 25, Issue 3, 609. – 17 p.](https://khavinson.info/assets/files/skan/2020-khavinson_diomede.pdf) DOI: 10.3390/molecules25030609 (2020)untag DOI:10.3390/molecules25030609 [PDF]

[74] Khavinson V.Kh., Tendler S.M., Vanyushin B.F., Kasyanenko N.A., Kvetnoy I.M., Linkova N.S., Ashapkin V.V., Polyakova V.O., Basharina V.S., Bernadotte A. Peptide Regulation of Gene Expression and Protein Synthesis in Bronchial Epithelium. // Lung. – 2014. – Vol. 192, Iss. 5. – P. 781-791. DOI: 10.1007/s00408-014-9620-7. (2014)untag DOI:10.1007/s00408-014-9620-7.](https://khavinson.info/assets/files/2014-Khavinson_Tendler1.pdf [PDF]

[118] Monaselidze J.R., Khavinson V.Kh., Gorgoshidze M.Z., Khachidze D.G., Lomidze E.M., Jokhadze T.A., Lezhava T.A. Effect of the Peptide Bronchogen (Ala-Asp-Glu-Leu) on DNA Thermostability. // Bulletin of Experimental Biology and Medicine. - 2011. - Vol. 150, N 3. - P. 375-377. (2011)untag [PDF]

[32] Sall T.S., Tarnovskaya S.I., Linkova N.S., Khavinson V.Kh. Effect of KE, EW, AEDG Peptides on Neuroendocrine System. // VI International symposium “Interactions of the Nervous and Immune Systems in Health and Disease”. – Russia, Saint Petersburg. – 2017. – Abstr. – P. 67-68. (2017)syn

Independent (non-Khavinson) studies

None catalogued. To date there are zero independent Western human trials of any Khavinson compound, in any year. Independent in-vitro data exists for Epitalon only (two 2025 studies). If a study belongs here, add it to non-khavinson-research.json and rebuild.

Reddit meta-scrape

No Reddit community discussion exists for this compound. This is honest reporting — the peptide has essentially zero anecdotal footprint in the biohacking community. Absence of anecdotes is not evidence of safety or efficacy, but it does mean there is no community-level signal to analyze.

Measurement protocol — concrete testable endpoints

Respiratory function (spirometry), TNF/inflammation markers.

All endpoints on one page: measurement-protocols.html · Evidence-tier legend: evidence-tiers.html